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1.
JAMA Pediatr ; 177(8): 859-860, 2023 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-37338901

RESUMO

This study examines the association between hospital consolidation and loss of pediatric inpatient services.


Assuntos
Hospitais , Pacientes Internados , Criança , Humanos
4.
Am J Emerg Med ; 61: 44-51, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-36037589

RESUMO

BACKGROUND: Following initial stabilization, critically ill children often require transfer to a specialized pediatric hospital. While the use of specialized pediatric transport teams has been associated with improved outcomes for these patients, the additional influence of transfer mode (helicopter or ground ambulance) on clinical outcomes remains unknown. METHODS: We investigated the association between transport mode and outcomes among critically ill children transferred to a single pediatric hospital via a specialized pediatric transport team. We designed a retrospective cohort study to reduce indication bias by limiting analysis to patients for whom a helicopter transport was initially requested. We compared outcomes for those who ultimately traveled via helicopter, and for those who ultimately traveled via ground ambulance due to non-clinical factors. RESULTS: We compared transport times, in-hospital mortality, and hospital length of stay by transport mode. Transport time in minutes was shorter for helicopter transports (median = 143, interquartile range [IQR]: 118-184) compared to ground ambulance transports (median = 289, IQR: 213-258; difference in medians = 146, 95% CI: 12 to 168, p < 0.001). In unadjusted analysis, helicopter transport was not associated with a difference in in-hospital mortality (helicopter = 6.0%, ground ambulance = 7.0%; 95% CI for difference: -6.6% to 3.3%; p = 0.64) but was associated with a statistically significant reduction in median hospital days (helicopter = 4, ground ambulance = 5; 95% CI -3 to 0; p = 0.04). In adjusted analyses, there were no statistically significant associations. These results were consistent across sensitivity analyses. CONCLUSIONS: Among critically ill pediatric patients without traumatic injuries transported by a specialty team, those patients who would have been transferred by helicopter if available but were instead transferred by ground ambulance reached their site of definitive care approximately 2.5 h later. Helicopter transport for these patients was not associated with in-hospital mortality, but was potentially associated with reduced hospital length of stay.


Assuntos
Resgate Aéreo , Humanos , Criança , Ambulâncias , Transporte de Pacientes/métodos , Centros de Traumatologia , Estudos Retrospectivos , Estado Terminal/terapia , Aeronaves , Hospitais Pediátricos
7.
J Athl Train ; 48(6): 810-7, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24143905

RESUMO

BACKGROUND: The knee joint is the second most commonly injured body site after the ankle and the leading cause of sport-related surgeries. Knee injuries, especially of the anterior cruciate ligament (ACL), are among the most economically costly sport injuries, frequently requiring expensive surgery and rehabilitation. OBJECTIVE: To investigate the epidemiology of ACL injuries among high school athletes by sport and sex. DESIGN: Descriptive epidemiology study. MAIN OUTCOME MEASURE(S): Using an Internet-based data-collection tool, Reporting Information Online (RIO), certified athletic trainers from 100 nationally representative US high schools reported athlete-exposure and injury data for athletes from 9 sports during the 2007/08-2011/12 academic years. The outcome of interest in this study was ACL injuries. RESULTS: During the study period, 617 ACL injuries were reported during 9 452 180 athlete exposures (AEs), for an injury rate of 6.5 per 100 000 AEs. Nationally, in the 9 sports studied, an estimated 215 628 ACL injuries occurred during the study period. The injury rate was higher in competition (17.6) than practice (2.4; rate ratio [RR] = 7.3, 95% confidence interval [CI] = 6.08, 8.68). Girls' soccer had the highest injury rate (12.2) followed by boys' football (11.1), with boys' basketball (2.3) and boys' baseball (0.7) having the lowest rates. In sex-comparable sports, girls had a higher rate (8.9) than boys (2.6; RR = 3.4, 95% CI = 2.64, 4.47). Overall, 76.6% of ACL injuries resulted in surgery. The most common mechanisms of injury were player-to-player contact (42.8%) and no contact (37.9%). CONCLUSIONS: Anterior cruciate ligament injury rates vary by sport, sex, and type of exposure. Recognizing such differences is important when evaluating the effectiveness of evidence-based, targeted prevention efforts.


Assuntos
Lesões do Ligamento Cruzado Anterior , Traumatismos em Atletas/epidemiologia , Traumatismos do Joelho/epidemiologia , Adolescente , Ligamento Cruzado Anterior/cirurgia , Atletas , Feminino , Humanos , Joelho/cirurgia , Traumatismos do Joelho/fisiopatologia , Traumatismos do Joelho/cirurgia , Articulação do Joelho/cirurgia , Masculino , Instituições Acadêmicas , Fatores Sexuais , Esportes , Estudantes
8.
Toxicol Lett ; 208(3): 293-9, 2012 Feb 05.
Artigo em Inglês | MEDLINE | ID: mdl-22119171

RESUMO

Human exposure to particulate matter (PM) elicits a variety of responses on the cardiovascular system through both direct and indirect pathways. Indirect effects of PM on the cardiovascular system are mediated through the autonomic nervous system, which controls heart rate variability, and inflammatory responses, which augment acute cardiovascular events and atherosclerosis. Recent research demonstrates that PM also affects the cardiovascular system directly by entry into the systemic circulation. This process causes myocardial dysfunction through mechanisms of reactive oxygen species production, calcium ion interference, and vascular dysfunction. In this review, we will present key evidence in both the direct and indirect pathways, suggest clinical applications of the current literature, and recommend directions for future research.


Assuntos
Poluentes Atmosféricos/toxicidade , Doenças Cardiovasculares/induzido quimicamente , Sistema Cardiovascular/efeitos dos fármacos , Material Particulado/toxicidade , Animais , Doenças Cardiovasculares/metabolismo , Humanos , Espécies Reativas de Oxigênio/metabolismo
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